Endocrine Abstracts

Introduction: Hypophysitis is a rare pituitary inflammation due to primary and secondary causes. Xanthomatous hypophysitis is the rarest subtype and described with lipid-laden cystic areas, transparent cytoplasmic and lipid-laden histiocytes and foamy (xanthomatous) histiocytes. Although the etiology of xanthomatous hypophysitis is not clearly known, it has been suggested to develop as a result of autoimmune cause or inflammatory process of infiltration of cyst components from...

Introductıon: Rathke’s cleft cysts (RCCs) are benign lesions originating from the epithelial remnants of Rathke’s pouch with a peak incidence at 30–50 years of age. It is detected at a rate of 13–33% in several autopsy series. RCC is usually asymptomatic and diagnosed incidentally. In symptomatic cases, common symptoms are headache, visual disturbance, and symptoms related to hypopituitarism.Case: A 28-year-old male patient prese...

Introduction: Acromegaly is a rare pathological condition characterized by excessive growth hormone (GH) secretion, leading to elevated levels of insulin-like growth factor 1 (IGF-1). According to the 2022 World Health Organization classification, GH-secreting pituitary adenomas fall under the PIT1-lineage. Pure GH-secreting adenomas selectively release growth hormone and may exhibit dense or sparse granulation patterns. Other subtypes include mammosomatotroph adenomas, mature...